How does Xanthigen work ?

From the results of the clinical study it is clear: Xanthigen is effective at helping promote weight loss, liver health, and a healthy body. How does it do this? There are indications that Xanthigen's effectiveness is based on improving metabolic rate and helping the liver shed fat. The results of previous studies suggest a unique mechanism by which the combination of pomegranate seed oil and fucoxanthin work. There is a growing body of evidence that fucoxanthin helps increase fat burning and helps reduce fat absorption in vivo, while pomegranate seed oil helps the liver to shed fats as well as increasing metabolism.

Brown seaweed extract standardized for fucoxanthin has demonstrated non-stimulant “thermogenic” properties. In other words, fucoxanthin increases how fast the body metabolizes calories, separate from any other effects. In animal studies, fucoxanthin has been shown to decrease the hormone leptin, increase adiponectin, increase the expression of the genes UCP-1, UCP-2, and UCP-3, which are thought to help increase fat-burning in fatty tissue, and decrease fat-building enzymes. Fucoxanthin increases the levels of UCP-1, a gene that increase fat burning in abdominal white adipose tissue (WAT), and increases fatty acid oxidation (“fat burning”) in WAT. Fucoxanthin decreased body fat mass as well as upregulating UCP-1. Fucoxanthin consumption has been shown to help enhance levels of DHA, an unsaturated fatty acid, in the liver. DHA, which stands for docosahexaenoic acid, is a polyunsaturated fatty acid that is important and beneficial for human health, although its role in the liver is unclear.

Pomegranate seed oil works in a complementary way. In vivo pomegranate seed oil decreases the accumulation of liver fat , a finding mirrored in clinical research on Xanthigen. However, although liver fat decreased, in this same study the total body fat was unchanged compared to the control. Thus pomegranate seed oil has shown a synergy with fucoxanthin, and may need fucoxanthin to fully realize its potential for healthy weight loss. An increase in Resting Energy Expenditure (REE) has also been shown in vivo and in the Xanthigen human study. The REE increase caused by fucoxanthin and pomegranate seed oil was not simply an additive effect – their separate activities combined for an even greater than expected REE boost.

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